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Oxidative Stress

Oxidative Stress


How much oxidative stress do you have in your body? With the new age of functional medicine, everyone is talking about oxidative damage. Oxidative damage increases your risk for certain ailments and disease states. Naturopathic doctors, Chiropractors, and other Practitioners have many interventions designed to treat oxidative stress. They administer treatments to increase your Glutathione and vitamin C, your body’s natural anti-oxidants. They are offered in many different forms including IV, intramuscular, subcutaneous and oral preparations.

My question has always been, how do they know who has oxidative damage and how much damage do they have? Certainly, one size cannot fit all patients! How do I know how many IV infusions I need until I have optimized and repaired the damage that has occurred in my body from all the pollutants, my own dastardly habits, the environment, food additives, plastics, the water I drink, radon gas and my heavy metal exposures?

The answer is easy!

Oxidation of DNA and RNA occurs most readily at the guanine residues. Measurement of these biomarkers in urine provides a quantitative assessment of oxidative stress. Although about 20 oxidative lesions in DNA have been identified to date, RNA is more sensitive to reactive oxygen species in part due to their compartmentalization in the cytosol as well as the nucleus. The most abundant lesion in DNA and RNA is 8-hydroxyguanosine (8-OHG); 8-OHG is the only measurable oxidized RNA lesion. With respect to oxidized DNA lesions, 8-hydroxy-2’-deoxyguanosine (8-OHdG) and it’s analog 8- hydroxyguanine are the most commonly studied and detected by-products of DNA damage that are excreted in the urine upon DNA repair. Urinary 8-OHdG and its analogs, 8-OHG and 8-hydroxyguanine, are sensitive biomarkers of oxidative stress and have been associated with many diseases, including bladder and prostate cancer, cystic fibrosis, atopic dermatitis, rheumatoid arthritis, Parkinson’s disease, Alzheimer’s and Huntington’s disease. Elevated levels of DNA and RNA damage have been measured in a wide range of neurological conditions.


Ok, that was not simple............I know.


Simply put, there is a test.


It’s super easy. You urinate in a cup. You freeze your urine and then ship to the company. You don’t need to go to a lab or your doctor's office. You collect in your own home. The instructions are easy to follow.

What you get from this simple test, can literally save your life!

Elevation in oxidative stress markers can be a warning sign of certain cancers that are developing in your body! Many other chronic diseases can also be detected earlier with this test.

This will certainly once and for all settle the question of how much oxidative stress you have in your body, making our interventions at Amethyst Wellness more specific to your own personal needs. It is less expensive to prevent chronic disease states before major symptoms occur. All diseases respond better when diagnosed early!

Our practitioners will then work with you, in person or by telephone to decide a best course of action based on your symptoms, history and physical and any other subsequent tests.

In functional medicine, one size does not fit all!


Call today 386-283-4180 for your free consultation and more information about the Oxidative Stress test.

Stay healthy,



Jerald Coopersmith, ARNP-BC Nurse Practitioner- certified in Family Medicine- ANCC

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